Positron emission tomography at Lawrence Berkeley Lab

by Ji Yeon Lee, Dr Suzanne Baker

Wednesday 28 Aug 2024, 12:00 → 13:00 US/Pacific

Auditorium (B50)

Abstract: Positron emission tomography (PET) is a nuclear medicine imaging technique that produces 3D images of functional processes in the body. Unlike MRI, PET illuminates a specific molecular target allowing for greater sensitivity and specificity. The imaging technique relies on radiotracers, molecules attached to radionuclides (usually Carbon-11, Fluorine-18, or Oxygen-15) that will bind a target of interest. The most commonly used radiotracer is Fluorodeoxyglucose, or sugar labeled with Fluorine-18. This is used to identify tumors which are highly metabolically active and take up the sugar allowing for precise localization tumors. Suzanne Baker and Ji Yeon Lee will review the physics of PET imaging and give an overview of the types of PET imaging done at LBL, including studies in aging and dementia and even a study performed on a plant. 

Dr. Suzanne Baker is a Senior Scientist at Lawrence Berkeley Labs the head of the Cellular and Tissue Imaging Department. Her work has focused on evaluation and the optimization of quantification of PET imaging related to Alzheimer's disease (AD). In AD, two proteins accumulate in the brain, amyloid and tau. PET has been used to measure amyloid in vivo since 2004 and tau since 2013.

 

Ji Yeon Lee graduated from University of the Pacific with a Masters in Engineering Science and started working at LBL in 2018 In 2022, Ji Yeon joined the Jagust lab where she analyzes neuroimaging data.

 

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Positron emission tomography (PET) is a nu